The fountain of youth is here at Plexus. We offer a range of age-reversing and internal rejuvenation regenerative medicine packages that bring back your youth! From improving hair density and reducing wrinkles, to improving agility, smoothening joints, and giving you that aha! feeling even at the age of 60.
Stem cell therapy can address various facets of aging, from cellular aging to age-related diseases. Let’s explore the role of stem cells used in anti-aging, and their potential to reverse aging, combat age-related diseases, and promote longevity.
What Causes Aging?
Let’s understand the biological processes of aging in detail.
Telomere Shortening
Telomeres are made from proteins and DNA sequences. These structures are found at the ends of chromosomes. With each cell division, telomeres naturally shorten. This ultimately affects the cell’s ability to replicate. Telomere shortening is an indicator of cellular aging. It leads to the aging of tissues as well as organs.
Cellular Senescence
This refers to the state in which the cells in our body lose their ability to divide and function the way they used to. Senescent cells are old cells, or aged cells. They accumulate over the years and lead to inflammation and tissue dysfunction.
Genomic Instability
Exposure to environmental toxins steadily damages DNA over a period of time. This leads to genomic instability and mutations, which increase the risk of cancer, and accelerate aging.
Mitochondrial Dysfunction
The powerhouse of the cell, the mitochondria can decline in function as we age. This can lead to reduced energy production, cellular damage, and oxidative stress.
Inflammation
Mostly chronic, this kind of low-grade inflammation is due to the release of inflammatory cytokines that trigger age-related changes and diseases.
Hormonal Changes
The biggest indicator of any change in our body is hormonal fluctuations. And as we age, hormone production and sensitivity are severely impacted. Decrease in sex hormones and growth hormones can impact bone density, muscle mass, and overall vigour.
Oxidative Stress
Free radicals and reactive oxygen species (ROS) damage cellular components, such as lipids, DNA, and proteins, leading to eventual aging and age-related diseases.
Impact of Aging on Different Body Systems
While most of us are concerned with increasing dark spots, dry skin, and fine lines near our eyes, aging does more harm than good to our overall well-being too. Let’s examine the impact of aging on our health.
Musculoskeletal System
- Gradual loss of muscle mass and bone density
- Increased frailty, risk of fractures and osteoporosis
Cardiovascular System
- Increased risk of cardiovascular diseases
- Thickening of blood vessel walls
- Poor heart function
Immune System
- Reduction in ability to fight infections and/or respond to vaccinations
Nervous System
- Changes in structure and function of neurons
- Cognitive decline
- Memory loss
- Increased risk of neurodegenerative diseases
Endocrine System
- Slower metabolism
- Lower energy levels
- Lack of sexual drive
Respiratory System
- Decreased lung function
- Increased susceptibility to respiratory infections
How Does Aging Impact Overall Appearance?
The impact of aging on our body’s systems and skin eventually causes changes in appearance too. Some of these changes are listed below:
- Skin changes
- Hair loss
- Grey hairs
- Brittle nails, prone to splitting and discolouration
- Increased body fat and decreased muscle mass
- Poor posture, increased risk of musculoskeletal issues
- Changes in facial features, specifically bone structure and fat distribution
- Loss of facial volume
- Changes in facial contours
What Does Aging Do to Our Skin?
Aging has a profound impact on our skin. It eventually leads to a range of visible changes in terms of texture and appearance of our skin. It is important to keep in mind that these changes occur due to both intrinsic (internal) and extrinsic (external) factors. Let’s look at the most common effects of aging on our skin:
Wrinkles and Fine Lines
Aging impacts the production of collagen and elastin in the skin, leading to the formation of wrinkles and fine lines.
Sagging and Loss of Tightness
Weakening of elastin fibres causes the skin to sag and become loose.
Dryness and Thinning
The production of sebum goes down significantly as we age. This causes our skin to become drier and thinner.
Hyperpigmentation and Age Spots
These are caused due to continuous exposure to UV rays and decline in melanin production.
Slower Wound Healing
The tissues’ ability to self-repair is impacted, causing skin wounds to take longer to heal.
Decreased Blood Flow
Paler and whiter (not brighter) complexion and slower wound healing are typical results of decreased blood flow to the skin.
Why are Stem Cells Used for Anti-Aging?
By contributing to tissue repair and regeneration, stem cells play a critical role in reversing the ageing process. Let’s look at their unique characteristics that make them effective agents in countering the effects of cellular and tissue changes.
Cellular Rejuvenation
Stem cells can differentiate into various cell types, including those that make up tissues and organs. They can replace damaged or dysfunctional cells, effectively rejuvenating the tissue and restoring its function.
Anti-Inflammatory Effects
Stem cells release anti-inflammatory factors, such as cytokines, and reduce chronic inflammation, which is a major contributor to aging.
Telomere Lengthening
Stem cells are capable of elongating telomeres in aging cells. This helps reverse cellular aging and promotes healthier cell function.
Immune System Modulation
Stem cells can modulate the immune system, and prevent the immune system from attacking healthy cells and tissues.
Secretome and Paracrine Signalling
Stem cells secrete a range of bioactive molecules that play a vital role in tissue repair, and regeneration.
Cellular Senescence
Stem cells eliminate senescent cells, and promote tissue regeneration and rejuvenation.
Can Stem Cell Therapy Combat Age-Related Diseases?
Yes! Plexus’ stem cell therapy for anti-aging can assist in symptom management, improve quality of life, and slow down the progression of the following age-related diseases:
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- Osteoarthritis
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- Cardiovascular diseases
- Neurodegenerative diseases
- Liver diseases
- Skin and hair appearance
- Muscle diseases
By reversing cellular aging, combating age-related diseases, and rejuvenating tissues, our customized stem cell therapy for anti-aging programs can enhance longevity and improve quality of life in old age.
Really, age is just a number!
FAQs
What is the best age for stem cell therapy?
The optimal ages for stem cell therapy are determined by the condition. Research indicates that stem cell therapy is more effective in younger patients when the body’s regenerative capacity is higher. However, at Plexus, we believe stem cell treatments do not have to be age-restricted.
How can we reduce aging?
Healthy lifestyle habits, including a balanced diet, regular exercise, stress management, and sufficient sleep, contribute to reducing the effects of aging. Bonus tip: Always wear sunscreen, even when you are not stepping out of home.
What is best for anti-aging?
A combination of skincare routines, a balanced diet rich in antioxidants, regular exercise, and proper hydration is most effective to slow down aging.
Which medicine is best for anti-aging?
No single medicine guarantees anti-aging effects. Retinoids, antioxidants, and other types of medications have been known to benefit skin health. Nevertheless, we urge you to consult your doctor or dermatologist before taking anti-aging medication, as these are based on individual needs, lifestyle factors and potential side effects.
