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Home / Disorders / Motor Neuron Disease

Everything you need to know about Motor Neuron Diseases

Did you know that each time you speak to your friend, go for a long walk, or chew your favorite food, your motor neurons coordinate all the muscle activities in your body? They send electrical output signals to the muscles, urging them to function in a coordinated manner. This helps you perform daily tasks such as gripping, walking, speaking, swallowing, and breathing.

When any damage occurs to the Motor Neurons, they lead to a variety of Motor Neuron Diseases. Understanding the disease thoroughly can help you seek the best treatment and rehabilitation from our Plexus centers in Bangalore and Hyderabad.

Before we proceed, let’s understand what motor neurons are. Motor neurons are specialized nerve cells which are responsible for sending messages to your body so that you can move. There are two main types of motor neurons-

Upper motor neurons are located in your brain. They send messages from there to your spinal cord.
Lower motor neurons are located in your spinal cord. They transmit the messages sent from your brain to your muscles.

Decoding Motor Neuron Diseases

Motor Neuron Diseases is a group of neurodegenerative disorders that occur when the motor neurons of the body are damaged. It results in the progressive deterioration of voluntary muscles.

As nerve cells die when you have a motor neuron disease, electrical messages can’t get from your brain to your muscles. Over time, the muscles become extremely weak. You may hear a doctor or therapist call this “atrophy.” When this happens, you lose control over movements. It gets harder to walk, talk, swallow, and breathe.

When any damage occurs to these cells, they lead to a variety of Motor Neuron Diseases. Understanding the disease thoroughly can help you seek the best treatment and rehabilitation from our Plexus centers in Bangalore and Hyderabad.

Symptoms of Motor Neuron Diseases

The symptoms of Motor Neuron Diseases begin gradually over weeks and months, sometimes starting on one side and then spreading throughout the body. As the disease progresses, individuals can have little or no movement that can lead to troubles in talking, breathing, and swallowing. Some of its common symptoms include:

Dragging of leg

Slurred speech (dysarthria)

Weakness in legs or shoulder

Cramps and muscles twitching

Footdrop caused by weak ankle muscles

Weakness in hands and grip, leading to difficulty in picking up or holding objects

Causes of Motor Neuron Diseases

There is no identifiable cause for Motor Neuron Diseases, and it is believed to be caused because of a combination of environmental, lifestyle, and genetic factors. Ongoing research has suggested the following causes:

Toxins
Environmental chemicals
Viral infections
Intense physical activity
Loss of growth factors to developing motor neurons
Mitochondrial dysfunction
Oxidative injury to neuron
Excessive excitability of neurons

Treatments for Motor Neuron Diseases

The type of treatment for MND depends on the severity of its symptoms. A lot can be done to ease your symptoms, maintain quality of life and keep you as mobile as possible for as long as possible. Some of the commonly prescribed treatments for Motor Neuron Disease include:

Cell Therapy

01 Cell Therapy

Cell Therapy has shown great promise in its ability to slow down disease progression, by providing a nurturing microenvironment to improve the status of diseased motor neurons to slow down neurodegeneration as well as prevent neuronal death – all of which have the potential to increase lifespan and quality of life.

Physical Therapy

02 Physical Therapy

Patients with Motor Neuron Diseases often face problems in walking, maintaining balance, and moving their shoulders and hands. Many patients even complain of severe pain in their limbs, especially their shoulders and legs. Physical therapy can help them improve posture, prevent joint immobility, and slow muscle weakness and atrophy with the help of a planned regimen of stretching and strengthening exercises.

Occupational Therapy

03 Occupational Therapy

Occupational therapists help to maintain strength, improve endurance, manage fatigue, train hand functions, reduce risk of falls and fall-related injuries and foster independence in daily life tasks and community mobility through a combination of various activities and adaptations.

Speech Therapy

04 Speech Therapy

Speech and swallowing difficulties are common in patients with Motor Neuron Diseases. Speech therapists help to maintain communication and swallowing skills for as long as possible, manage symptoms, and adopt compensatory strategies for loss of function.

Our treatment program at Plexus

At Plexus, we provide a curated treatment plan to help you manage your symptoms for Motor Neuron Diseases. Under the guided supervision of Dr Na’eem Sadiq, we provide the most advanced Cell Therapy along with a customized intensive rehabilitation program that includes Occupational Therapy, Physiotherapy, and Speech Therapy.

Our team uses a wide range of rehabilitation techniques to slow the progression of the disease and make it easier to manage the symptoms, including:

Endurance training

Dysphagia management

Hand function training

Strengthening of oral structures

Strength training of upper limbs and lower limbs

Stretching to improve joint mobility

Functional splinting

Functional stretching

ADL training

What our patients say

Aman Kumar (name changed)

I was experiencing weakness in my hands and legs for more than a year. No doctor could identify what I was exactly suffering from. I was put on Vitamin tablets. At Plexus Dr Na'eem Sadiq diagnosed me with Motor Neuron Disease and properly explained the condition to me. I have received Cell Therapy along with rehabilitation services. I believe you will find the best Physiotherapy and Occupational therapy services at their centers. I have learnt all the exercises that I need to do and I am extremely positive that I have received the best form of treatment and at the right place."

Rahul Khanna (name changed)

“I came to Plexus for MND treatment. Dr Na’eem Sadiq understood my problem and gave me the best possible treatment. The staff was extremely friendly and the treating team is very knowledgeable. I would recommend all MND patients to visit Plexus and get treated. Thank you team."

FAQs answered

Is Motor Neuron Disease inherited?

There is no family history involved in the majority of cases for Motor Neuron Disease However, a variety of genetic and environmental factors may be involved in causing the disorder in certain individuals.

Which functions are not affected by Motor Neuron Disease?

Our senses are usually not impaired by Motor Neuron Disease, so patients can still see, hear, taste, smell, and feel sensations. Although, some people can experience taste changes, skin hypersensitivity, or temperature regulation problems.

Bladder and bowel movements are also generally not affected by the disease. However, individuals with Motor Neuron Disease may find it difficult to use the washroom due to impaired mobility. Dehydration may also set in with reduced movements, leading to constipation. Motor Neuron Disease may also not affect their libido, however, sexual expression may become difficult due to lack of mobility.