Importance of Cells

Since its discovery in 1950, Autologous Bone Marrow Derived Cells have been considered as the ultimate breakthrough in modern medicine. The importance of Autologous Bone Marrow Derived Cells can never be underestimated. Its ability to repair and/or restore damaged, diseased, or dysfunctional tissue gives hope to patients with varying health conditions and their loved ones.

Plexus Neuro and Cell Research Centre offers the best regenerative rehabilitation in India. Founded by Dr. Na’eem Sadiq, India’s no. 1 Cell specialist, Plexus uses only autologous mesenchymal Cells taken from the patient’s own body as part of our rehabilitation program.

But what is autologous Cell therapy? What are mesenchymal Cells? How does a patient suffering from neurological conditions like Parkinson’s, Erb’s Palsy, or even a spinal cord injury benefit from Cell therapy? Just how important is Cell therapy?

Read on to find out.

What are Regenerative Cells?

Regenerative cells are progenitor cells that can transform and/or multiply into specialized cells.

Through a laboratory procedure known as differentiation, Cells procured from one part of the body can become/grow into other kinds of cells.

Regenerative cells are the very foundation of every tissue/organ in the human body. The cells in our body have specific roles and functions. Regenerative cells, on the other hand, are undifferentiated cells that can turn into specific types of cells that our body requires.

What is Cell therapy?

Cell therapy, alternatively known as regenerative medicine, helps in repairing or restoring function of diseased, dysfunctional, and/or injured tissue by injecting Autologous Bone Marrow Derived Cells(or their derivatives). Injected Autologous Bone Marrow Derived Cells provide immunomodulation, secrete growth factors, reduce inflammation, as well as generate supporting cells that protect damaged motor neurons from further deterioration.

Neuroprotection is one of the primary objectives of regenerative treatments like Cell therapy. The two types of Cell therapy include:

Autologous therapy : the patient is treated with cells procured from their own bone marrow, blood, or fat tissue

Allogeneic therapy : the patient is treated with cells from external donors

Types of Regenerative Cells and Potential Therapies

Embryonic Autologous Cell Therapy

Also known as pluripotent regenerative cells, embryonic regenerative cells are derived from the inner cell mass of an embryo in its early stages of development. These cells are usually grown in laboratory conditions. They are derived from unused embryos that are from an IVF procedure. Embryonic autologous cells are pluripotent, meaning they are unspecialized cells that do not have any specific characteristics like shape, or gene expression pattern. These regenerative cells can be differentiated into any cell type in the body.

Adult Regenerative Cell Therapy

These are undifferentiated autologous tissue-derived regenerative cells procured from fully developed tissues like the brain, bone marrow, etc. Since adult regenerative cells are multipotent, they have limited ability to differentiate into other types of cells. For instance, regenerative cells from the liver are most likely to make liver cells only. However, these regenerative cells play an important role in maintaining the integrity of the tissue in which they are found. Adult regenerative cells can be used for tissue repair and regenerative medicine.

Induced Pluripotent Regenerative Cell Therapy

These regenerative cells have been genetically reprogrammed to exhibit the characteristics of embryonic regenerative cells. Induced pluripotent regenerative cells are generated by introducing specific types of genes into adult regenerative cells. These reprogrammed cells can self-renew and also differentiate into any cell type in the body.

Since induced pluripotent regenerative cells are generated from the patient’s own cells, it significantly reduces the risk of immune rejection.

Mesenchymal Regenerative Cell Therapy

These are adult tissue-derived mesenchymal regenerative cells. They display anti-inflammatory, immunomodulatory, self-renewal, cell-division, signaling, and differentiation properties. They have the ability to divide and develop into many specialized cell types in specific organs and/or tissues. They can even become unique cell types and can create more regenerative cells when cultured in a laboratory. Mesenchymal regenerative cells can replace cells that are diseased or damaged.

Mesenchymal regenerative cells are sourced from different types of tissue, like adipose (fat) tissue, autologous bone marrow, blood, dental pulp, umbilical cord tissue, liver, and skin.

The first mesenchymal regenerative cells were found in the bone marrow and were capable of making bone, cartilage, and even fat cells.

Mesenchymal regenerative cell transplantation can help slow down the rate of degeneration caused by MND, Parkinson’s and other illnesses.

Cell therapy at Plexus

At Plexus, India’s first ISO-Certified Cell research center, the regenerative cell procedure
involves the following steps:

Step 1: Review the patient’s medical history

Step 2: Thorough physical examination of patient by a panel of Cell consultants

Step 3: Patient’s eligibility for Cell therapy is ascertained

Step 4: Cells are procured from the patient’s bone marrow; this procedure is performed under local anesthesia

Step 5: Collected Cells are prepared sent to the laboratory for quality checks and isolated for further therapy

Step 6: Patient is discharged

Step 7: The isolated regenerative cells divide and form daughter cells which can either self-renew or turn into specialized cells like brain cells, bone cells,

Step 8: Further course of treatment is determined

Advantages of Cell therapy at Plexus

Cell therapy has the following benefits:

Enhanced everyday functioning
Improved quality of life
Immune system modulation and reduction of inflammation
Prevention of further nerve damage
Speedy recovery post-procedure
Non-surgical procedure
Zero complications and side-effects

Plexus Neuro and Cell Research Centre uses autologous mesenchymal Cells taken from the patient’s own body. The procedure is conducted by Dr. Sadiq, India’s no. 1 Cell specialist, and his team of highly-skilled and experienced Cell specialists.

FAQs

What is the most useful regenerative cell?

Pluripotent Cells are procured from an early embryo and have the ability to differentiate into almost any cell type. They are believed to be the most useful regenerative cells.

How valuable are regenerative cells?

A regenerative cell can be regarded as the body’s raw material. It is from these cells that other specialized cells are generated. These specialized cells have their own function and ability. Cells are the very foundation of our existence. So, one can imagine just how valuable and beneficial they can be when it comes to giving patients suffering from neurological conditions like Parkinson’s, Erb’s Palsy, Multiple Sclerosis, etc. a new lease on life.

What are the features of regenerative cells?

The two main defining features of regenerative cells are the ability to differentiate into a specialized adult cell type and perpetual self-renewal.

What is the future of regenerative cells?

Regenerative cells have the potential to grow into new tissue. Scientists and medical researchers also believe Cells can be used to generate new organs (that can be transplanted). The future of regenerative cells lies in their limitless potential.