Since its discovery in 1950, Cells have been considered as the ultimate breakthrough in modern medicine. The importance of Cells can never be underestimated. Its ability to repair and/or restore damaged, diseased, or dysfunctional tissue gives hope to patients with varying health conditions and their loved ones.
Plexus Neuro and Cell Research Centre offers the best regenerative rehabilitation in India. Founded by Dr. Na’eem Sadiq, India’s no. 1 Cell specialist, Plexus uses only autologous mesenchymal Cells taken from the patient’s own body as part of our rehabilitation program.
But what is autologous Cell therapy? What are mesenchymal Cells? How does a patient suffering from neurological conditions like Parkinson’s, Erb’s Palsy, or even a spinal cord injury benefit from Cell therapy? Just how important is Cell therapy?
Read on to find out.
What are Cells?
Cells are progenitor cells that can transform and/or multiply into specialized cells.
Through a laboratory procedure known as differentiation, Cells procured from one part of the body can become/grow into other kinds of cells.
Cells are the very foundation of every tissue/organ in the human body. The cells in our body have specific roles and functions. Cells, on the other hand, are undifferentiated cells that can turn into specific types of cells that our body requires.
What is Cell therapy?
Cell therapy, alternatively known as regenerative medicine, helps in repairing or restoring function of diseased, dysfunctional, and/or injured tissue by injecting Cells (or their derivatives). Injected Cells provide immunomodulation, secrete growth factors, reduce inflammation, as well as generate supporting cells that protect damaged motor neurons from further deterioration.
Neuroprotection is one of the primary objectives of regenerative treatments like Cell therapy. The two types of Cell therapy include:
Autologous therapy : the patient is treated with cells procured from their own bone marrow, blood, or fat tissue
Allogeneic therapy : the patient is treated with cells from external donors
Types of Cells and potential therapies
Embryonic Cells therapy
Also known as pluripotent Cells, embryonic Cells (ESCs) are derived from the inner cell mass of an embryo in its early stages of development. These cells are usually grown in laboratory conditions. ESCs are derived from unused embryos that are from an IVF procedure. The embryonic Cells are pluripotent, meaning they are unspecialized cells that do not have any specific characteristics like shape, or gene expression pattern. These cells can be differentiated into any cell type in the body.
Adult Cells therapy
These are undifferentiated cells procured from fully developed tissues like the brain, bone marrow, etc. Since adult Cells (ASCs) are multipotent cells, they have limited ability to differentiate into other types of cells. For instance, Cells from the liver are most likely to make liver cells only. However, these cells play an important role in maintaining the integrity of the tissue in which they are found. ASCs can be used for tissue repair and regenerative medicine.
Induced pluripotent cells therapy
These cells have been genetically reprogrammed to exhibit the characteristics of embryonic Cells. Induced pluripotent Cells (iPSCs) are generated by introducing specific types of genes into adult cells. iPSCs can self-renew and also differentiate into any cell type in the body.
Since iPSCs are generated from the patient’s own cells, it significantly reduces the risk of immune rejection.
Mesenchymal adult Cells therapy
These are adult Cells. They display anti-inflammatory, immunomodulatory, self-renewal, cell-division, signaling, and differentiation properties. They have the ability to divide and develop into many specialized cell types in specific organs and/or tissues. They can even become unique Cell types and can create more Cells when cultured in a laboratory. Mesenchymal adult Cells (MSCs) can replace cells that are diseased or damaged.
MSCs are sourced from different types of tissue, like adipose (fat) tissue, bone marrow, blood, dental pulp, umbilical cord tissue, liver, and skin.
The first MSCs were found in the bone marrow and were capable of making bone, cartilage, and even fat cells.
Mesenchymal Cell transplantation can help slow down the rate of degeneration caused by MND, Parkinson’s and other illnesses.
Cell therapy at Plexus
At Plexus, India’s first ISO-Certified Cell research center, the Cell procedure involves the following steps:
Step 1: Review the patient’s medical history
Step 2: Thorough physical examination of patient by a panel of Cell consultants
Step 3: Patient’s eligibility for Cell therapy is ascertained
Step 4: Cells are procured from the patient’s bone marrow; this procedure is performed under local anesthesia
Step 5: Collected Cells are prepared sent to the laboratory for quality checks and isolated for further therapy
Step 6: Patient is discharged
Step 7: The isolated Cells divide and form daughter cells which can either self-renew or turn into specialized cells like brain cells, bone cells,
Step 8: Further course of treatment is determined
Advantages of Cell therapy at Plexus
Cell therapy has the following benefits:
- Enhanced everyday functioning
- Improved quality of life
- Immune system modulation and reduction of inflammation
- Prevention of further nerve damage
- Speedy recovery post-procedure
- Non-surgical procedure
- Zero complications and side-effects
Plexus Neuro and Cell Research Centre uses autologous mesenchymal Cells taken from the patient’s own body. The procedure is conducted by Dr. Sadiq, India’s no. 1 Cell specialist, and his team of highly-skilled and experienced Cell specialists.
FAQs
What is the most useful Cell?
Pluripotent Cells are procured from an early embryo and have the ability to differentiate into almost any cell type. They are believed to be the most useful Cells.
How valuable are Cells?
A Cell can be regarded as the body’s raw material. It is from these cells that other specialized cells are generated. These specialized cells have their own function and ability. Cells are the very foundation of our existence. So, one can imagine just how valuable and beneficial they can be when it comes to giving patients suffering from neurological conditions like Parkinson’s, Erb’s Palsy, Multiple Sclerosis, etc. a new lease on life.
What are the features of Cells?
The two main defining features of Cells are the ability to differentiate into a specialized adult cell type and perpetual self-renewal.
What is the future of Cells?
Cells have the potential to grow into new tissue. Scientists and medical researchers also believe Cells can be used to generate new organs (that can be transplanted). The future of Cells lies in their limitless potential.
What is the source of Cells?
There are four main sources of Cells. They are:
- Embryonic tissues
- Fetal tissues
- Adult tissues
- Differentiated somatic cells
